{"id":366,"date":"2020-03-06T20:30:05","date_gmt":"2020-03-06T20:30:05","guid":{"rendered":"http:\/\/liverandpancreasclinic.com\/blog\/?p=366"},"modified":"2020-03-06T20:30:06","modified_gmt":"2020-03-06T20:30:06","slug":"what-is-a-pnet","status":"publish","type":"post","link":"https:\/\/liverandpancreasclinic.com\/blog\/2020\/03\/06\/what-is-a-pnet\/","title":{"rendered":"What is a PNET ( Pancreatic neuroendocrine tumors)?"},"content":{"rendered":"\n<p>NET stands for neuroendocrine tumor. Neuroendocrine cells are special types of cells commonly located in the linings of gastrointestinal tract (esophagus to rectum), bronchus (airway) and pancreas. They are located elsewhere too. <a href=\"http:\/\/liverandpancreasclinic.com\/blog\/2018\/12\/15\/what-is-cancer\/\">Tumor <\/a>arising from these cells is called a neuroendocrine tumor or NET. The neuroendocrine cells secrete various hormones depending on their location. However not all NETs secrete tumors. Those that secrete hormones present due to the various effects of these hormones.<\/p>\n\n\n\n<p>PNETs short for pancreatic neuroendocrine tumors. These\ntumors may arise from the endocrine cells in the islets of Langerhans in the\npancreas (islet cell tumors) or so called neuroendocrine cells either in the\npancreas or ampulla of Vater (carcinoid tumors) or the duodenum (gastrinomas).\nThe success rate of treatment of these PNETs is much better than the results of\ntreatment of other types of pancreatic cancer.<\/p>\n\n\n\n<p>PNETs can secrete one of six or more different hormones\ncausing different types of illness (or syndrome) and are called functioning\nneuro- endocrine tumors. Also neuroendocrine tumors may not secret any hormones\nand are then called non-functioning neuroendocrine tumors. Endocrine tumors can\naffect individuals at any age and they can even arise in small babies.<\/p>\n\n\n\n<p>Tumors that release excess insulin are called insulinoma.\nThese tumors are nearly always benign, meaning non-malignant and non-\ncancerous. Tumors that release excess gastrin are called gastrinoma and occur\nin the pancreas and in the duodenum. These tumors are mostly cancerous. Other\ntypes of functioning neuro- endocrine tumors are called glucagonomas, VIPomas,\nsomatostatinomas &amp; PPomas and are usually malignant or cancerous.<\/p>\n\n\n\n<p>PNETs may be inherited and the two main types of hereditary pancreatic neuroendocrine tumors are found in multiple endocrine neoplasia type 1 (MEN-1) &amp; von Hippel-Lindau disease (VHL), but also in the rare disorders of neuro- fibromatosis type 1 and tuberous sclerosis.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Facing pancreatic neuroendocrine tumors?<\/h2>\n\n\n\n<p>Consult the best <a href=\"http:\/\/liverandpancreasclinic.com\/liver-pancreas-surgeon.php\">Pancreatic Cancer Specialist in Mumbai<\/a>.  <strong><a href=\"http:\/\/liverandpancreasclinic.com\/liver-pancreas-surgeon.php\">Dr. D. R. Kulkarni<\/a><\/strong> is an eminent  <a href=\"http:\/\/liverandpancreasclinic.com\/liver-pancreas-surgeon.php\">Pancreatic Cancer<\/a><strong><a href=\"http:\/\/liverandpancreasclinic.com\/liver-pancreas-surgeon.php\"> Surgeon<\/a><\/strong> in Mumbai, India. He has 24 years experience in the field of  Pancreatic Cancer Surgery.  For Appointments call on : <a href=\"tel:09821046391\">9821046391<\/a> or click here to <a rel=\"noreferrer noopener\" href=\"http:\/\/www.liverandpancreasclinic.com\/contact-liver-and-pancreas-surgeon.php\" target=\"_blank\">Book an appointment online<\/a> <\/p>\n","protected":false},"excerpt":{"rendered":"<p>NET stands for neuroendocrine tumor. Neuroendocrine cells are special types of cells commonly located in the linings of gastrointestinal tract (esophagus to rectum), bronchus (airway) and pancreas. They are located elsewhere too. Tumor arising from these cells is called a neuroendocrine tumor or NET. The neuroendocrine cells secrete various hormones&#8230;<\/p>\n","protected":false},"author":1,"featured_media":369,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[40,41,1],"tags":[],"yst_prominent_words":[],"class_list":["post-366","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","category-pancreatic-tumors","category-uncategorized","loop-entry clr boxed"],"_links":{"self":[{"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/posts\/366","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/comments?post=366"}],"version-history":[{"count":7,"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/posts\/366\/revisions"}],"predecessor-version":[{"id":374,"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/posts\/366\/revisions\/374"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/media\/369"}],"wp:attachment":[{"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/media?parent=366"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/categories?post=366"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/tags?post=366"},{"taxonomy":"yst_prominent_words","embeddable":true,"href":"https:\/\/liverandpancreasclinic.com\/blog\/wp-json\/wp\/v2\/yst_prominent_words?post=366"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}